Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 180
interventional 147
Observational 32
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 57
Procedure 14
Device 11
Drug|placebo 11
Drug|Other 6
Other 6
Device|Procedure 4
Drug|Procedure 4
Behavioral 3
Biological 3
Biological|Drug 3
Radiation 3
Biological|Drug|Other 2
Device|Drug 2
Drug|Other|placebo 2
placebo|Procedure 2
Behavioral|Other 1
Biological|Drug|Other|Radiation 1
Biological|Other 1
Biological|Procedure 1
Combination Product|placebo 1
Diagnostic Test 1
Dietary Supplement|Drug|placebo 1
Dietary Supplement|Procedure 1
Dietary Supplement|Radiation 1
Drug|Other|Procedure 1
Drug|placebo|Procedure 1
Drug|Radiation 1
Genetic 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 70
NA 10
Australia 7
United Kingdom 7
France 6
Netherlands 6
Denmark 5
Germany 4
Canada 3
Argentina|Australia|Austria|Belgium|Bosnia and Herzegovina|Brazil|Bulgaria|Canada|Colombia|Croatia|Czechia|Denmark|Finland|France|Germany|Greece|Hungary|Ireland|Israel|Italy|Lithuania|Mexico|Netherlands|New Zealand|Norway|Poland|Portugal|Romania|Russian Federation|Serbia|Slovakia|Slovenia|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
Australia|New Zealand 1
Austria 1
Austria|Belgium|Canada|Germany 1
Austria|Belgium|Finland|France|Italy|Sweden|United Kingdom 1
Austria|Switzerland 1
Belgium 1
Brazil 1
Canada|United States|Australia|Puerto Rico 1
China 1
Denmark|Germany|Norway|Sweden|United Kingdom 1
Finland 1
France|United States|Austria|Canada|Germany|Italy|Mexico|Netherlands|Russian Federation|Spain 1
Greece 1
Hong Kong|Japan|Taiwan 1
Israel 1
Italy 1
Korea, Republic of 1
Norway 1
Switzerland 1
Taiwan 1
United States|Australia|Belgium|Canada|France|Germany|Greece|Hungary|Italy|Spain|Switzerland|United Kingdom 1
United States|Australia|Belgium|France|Germany|United Kingdom 1
United States|Austria|Belgium|Canada|France|Germany|Greece|Italy|Spain|Switzerland 1
United States|Belgium|Canada|Denmark|France|Germany|Italy|Netherlands|Spain|United Kingdom 1
United States|Canada 1
United States|Netherlands|Switzerland|United Kingdom 1
United States|Puerto Rico 1
United States|Spain|Switzerland|United Kingdom 1

Sites per Study

Site_count Study_Count
1 91
2 8
3 8
4 4
5 5
6 1
7 4
9 4
10 3
11 2
12 2
13 1
14 1
16 1
17 2
18 1
21 1
35 1
49 1
58 1
62 1
68 1
173 1
181 1
938 1

Phase

Phase Study_Count
N/A 41
Phase 2 40
Phase 1 29
Phase 3 15
Phase 1/Phase 2 10
Phase 4 6
Early Phase 1 4
Phase 2/Phase 3 2

Number of Arms

Number_of_Arms Count_of_Studies
1 65
2 47
3 13
4 7
5 2
8 1
NA 12

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 4.00 9.0000 4.00000 5.0 3.000 42.00 14.0 15.0000
1st Qu. 4.75 28.0000 20.00000 17.0 25.500 43.25 73.5 31.2500
Median 7.00 50.0000 30.00000 22.5 40.000 44.50 120.0 42.0000
Mean 8.25 513.4146 38.51724 49.9 107.275 44.50 191.2 197.1667
3rd Qu. 10.50 179.0000 45.00000 56.5 100.000 45.75 171.5 87.2500
Max. 15.00 14381.0000 154.00000 186.0 1232.000 47.00 1131.0 954.0000

Trial Group Type

group_type Group_Count
Experimental 152
Active Comparator 47
Placebo Comparator 27
NA 12
No Intervention 11
Other 6
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Single Group Assignment 70
Parallel Assignment 69
Sequential Assignment 4
Crossover Assignment 2
Factorial Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 115
Diagnostic 11
Supportive Care 7
Prevention 6
Basic Science 2
Health Services Research 2
NA 2
Other 1
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 14
NA 4
Germany 3
France 2
United Kingdom 2
France|Germany|Italy|United Kingdom 1
Germany|Switzerland 1
Greece 1
Israel 1
Netherlands 1
Norway 1
Sweden 1

Sites per Study

Site_count Study_Count
1 24
2 2
4 3
17 1
34 1
42 1

Enrollment Metrics

Measure Observational
Min 7.0000
1st Qu 62.7500
Median 114.0000
Mean 528.6562
3rd Qu 210.0000
Max 9000.0000

Observation Model

observational_model Study_Count
Cohort 18
Case-Only 6
Case-Control 2
Case Control 2
NA 2
Family-Based 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 26
Cross-Sectional 3
Retrospective 2
NA 1

Registries

Studies by Country

Country Study_Count
Spain 1

Sites per Study

Site_count Study_Count
15 1

Enrollment Metrics

Measure Registries
Min 6000
1st Qu 6000
Median 6000
Mean 6000
3rd Qu 6000
Max 6000

Registry Model

observational_model Study_Count
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
4 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04323202 Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N https://ClinicalTrials.gov/show/NCT04323202 Recruiting Case Comprehensive Cancer Center 2021-06-15
NCT03237013 Strategies to Promote Skin Health https://ClinicalTrials.gov/show/NCT03237013 Completed San Diego State University 2016-12-14
NCT03180528 Topical Remetinostat in Treating Patient With Cutaneous Basal Cell Cancer https://ClinicalTrials.gov/show/NCT03180528 Active, not recruiting Stanford University 2020-06-28
NCT03167762 Photographing the Skin During Photodynamic Therapy https://ClinicalTrials.gov/show/NCT03167762 Enrolling by invitation University of Dundee 2020-06-01
NCT03132636 PD-1 in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy https://ClinicalTrials.gov/show/NCT03132636 Active, not recruiting Regeneron Pharmaceuticals 2021-10-14
NCT03035188 Neoadjuvant Vismodegib in Patients With Large and/or Recurrent Resectable Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT03035188 Active, not recruiting SRH Wald-Klinikum Gera GmbH 2019-12-31
NCT03012009 Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT03012009 Completed University Hospital, Ghent 2017-05-31
NCT02978625 Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers https://ClinicalTrials.gov/show/NCT02978625 Recruiting National Cancer Institute (NCI) 2021-06-01
NCT02939027 Study of Electronic Brachytherapy for Cutaneous Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02939027 Completed Instituto de Investigacion Sanitaria La Fe 2016-07-31
NCT02902822 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo https://ClinicalTrials.gov/show/NCT02902822 Completed Centro Studi Gised 2019-05-31
NCT02828111 Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas https://ClinicalTrials.gov/show/NCT02828111 Completed PellePharm, Inc. 2017-11-09
NCT02762084 Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients https://ClinicalTrials.gov/show/NCT02762084 Completed PellePharm, Inc. 2017-04-24
NCT02735356 Topical Itraconazole in Treating Patients With Basal Cell Cancer https://ClinicalTrials.gov/show/NCT02735356 Completed Stanford University 2017-09-19
NCT02690948 Pembrolizumab With or Without Vismodegib in Treating Metastatic or Unresectable Basal Cell Skin Cancer https://ClinicalTrials.gov/show/NCT02690948 Completed Stanford University 2017-11-30
NCT02668614 Early Detection of Skin Cancer With Sensor Technology https://ClinicalTrials.gov/show/NCT02668614 Completed Lawson Health Research Institute 2018-02-28
NCT02667574 Study Evaluating the Interest of Vismodegib as Neo-adjuvant Treatment of Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT02667574 Active, not recruiting University Hospital, Lille 2019-12-31
NCT02662244 Long-pulsed 1064 nm Nd:YAG Laser Treatment of Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02662244 Completed University of California, San Diego 2016-09-30
NCT02639117 Photodynamic Therapy and Vismodegib for Multiple Basal Cell Carcinomas https://ClinicalTrials.gov/show/NCT02639117 Completed University of Arizona 2016-11-02
NCT02623101 Reflectance Confocal Microscopy in Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02623101 Completed Radboud University 2019-05-31
NCT02587819 Investigation of the Safety and Tolerability of BSCT (Anti-nf-P2X7) 10% Ointment https://ClinicalTrials.gov/show/NCT02587819 Completed Biosceptre 2013-10-31
NCT02580916 Utility of the Skin Cancer Quality of Life Impact Tool https://ClinicalTrials.gov/show/NCT02580916 Completed Oxford University Hospitals NHS Trust 2017-08-31
NCT02550678 A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02550678 Completed Ascend Biopharmaceuticals Ltd 2017-11-30
NCT02436408 VISmodegib for ORbital and Periocular Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02436408 Active, not recruiting University of Michigan Rogel Cancer Center 2021-03-31
NCT02409628 EktoTherixâ„¢ Regenerative Tissue Scaffold for Repair of Surgical Excision Wounds https://ClinicalTrials.gov/show/NCT02409628 Completed Neotherix Limited 2017-07-31
NCT02367547 Superficial Basal Cell Cancer’s Photodynamic Therapy: Comparing Three Photosensitizers: HAL and BF-200 ALA Versus MAL https://ClinicalTrials.gov/show/NCT02367547 Active, not recruiting Joint Authority for Päijät-Häme Social and Health Care 2018-09-30
NCT02354261 Open-label Trial of SUBAâ„¢-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS) https://ClinicalTrials.gov/show/NCT02354261 Active, not recruiting HedgePath Pharmaceuticals, Inc. 2019-03-31
NCT02352428 Skin Cancer Screening Education Study https://ClinicalTrials.gov/show/NCT02352428 Active, not recruiting Association of Dermatological Prevention, Germany 2018-12-31
NCT02285790 One-stop-shop Study for Treatment of Basal Cell Carcinoma Using Reflectance Confocal Microscopy https://ClinicalTrials.gov/show/NCT02285790 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2015-10-31
NCT02270645 Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser https://ClinicalTrials.gov/show/NCT02270645 Completed University of Miami 2017-06-30
NCT02242929 Surgery Versus Combined Treatment With Curettage and Imiquimod for Nodular Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02242929 Active, not recruiting Maastricht University Medical Center 2017-12-31
NCT02144077 Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic Therapy https://ClinicalTrials.gov/show/NCT02144077 Active, not recruiting Biofrontera Bioscience GmbH 2015-11-30
NCT02125669 Pulsed Dye Laser in Treating Superficial Basal Cell Carcinomas https://ClinicalTrials.gov/show/NCT02125669 Completed Hautklinik Darmstadt 2013-09-30
NCT02123511 Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy https://ClinicalTrials.gov/show/NCT02123511 Completed Mayo Clinic 2016-03-22
NCT02120677 Topical Itraconazole in the Treatment of Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02120677 Completed Johns Hopkins University 2019-01-30
NCT01298167 Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery https://ClinicalTrials.gov/show/NCT01298167 Completed Yale University 2011-08-31
NCT01292668 Photodynamic Therapy Using Methyl-5-Aminolevulinate Hydrochloride Cream in Determining Pain Threshold in Patients With Skin Cancer https://ClinicalTrials.gov/show/NCT01292668 Completed Roswell Park Cancer Institute 2012-07-31
NCT02029352 Topical Green Tea Ointment in Treatment of Superficial Skin Cancer https://ClinicalTrials.gov/show/NCT02029352 Completed Maastricht University Medical Center 2015-09-30
NCT03897036 Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT03897036 Recruiting Senhwa Biosciences, Inc. 2020-07-31
NCT02018679 Er:YAG Ablative Fractional Laser Assisted-Photodynamic Therapy Versus Photodynamic Therapy for Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02018679 Completed Dong-A University 2013-02-28
NCT02017964 Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma https://ClinicalTrials.gov/show/NCT02017964 Active, not recruiting Children’s Oncology Group 2018-03-31
NCT02007317 Safety and Efficacy of Oshadi D and Oshadi R in Basal Cell Carcinoma Patients Prior to Tumor Excision a Phase 2 Study https://ClinicalTrials.gov/show/NCT02007317 Completed Oshadi Drug Administration 2017-03-31
NCT01980264 Harmonics-based in Vivo Optical Virtual Biopsy https://ClinicalTrials.gov/show/NCT01980264 Recruiting National Taiwan University Hospital 2020-12-31
NCT01835626 Phase II Study of Radiation Therapy and Vismodegib for Advanced Head/Neck Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01835626 Completed University of California, San Francisco 2019-09-10
NCT01815840 A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas https://ClinicalTrials.gov/show/NCT01815840 Completed Hoffmann-La Roche 2015-08-27
NCT01806675 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy https://ClinicalTrials.gov/show/NCT01806675 Completed Stanford University 2016-12-07
NCT01791894 Arsenic Trioxide in Treating Patients With Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01791894 Completed Stanford University 2013-11-30
NCT01773447 Set-back Suture Versus Traditional Vertical Mattress Suture https://ClinicalTrials.gov/show/NCT01773447 Completed University of California, Davis 2014-03-31
NCT01700049 Study Evaluating the Efficacy of Oral Vismodegib in Various Histologic Subtypes https://ClinicalTrials.gov/show/NCT01700049 Completed Mayo Clinic 2017-07-03
NCT01637194 Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01637194 Completed Fox Chase Cancer Center 2011-07-31
NCT01631331 Vismodegib in Treating Patients With Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT01631331 Completed Stanford University 2015-09-17
NCT01609179 IPI-926 Extension Protocol for Continuation of Treatment With IPI-926 https://ClinicalTrials.gov/show/NCT01609179 Completed Infinity Pharmaceuticals, Inc. 2012-10-31
NCT01556009 Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas https://ClinicalTrials.gov/show/NCT01556009 Completed UCSF Benioff Children’s Hospital Oakland 2015-12-31
NCT01543581 Vismodegib for Treatment of Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01543581 Completed Loma Linda University 2013-06-30
NCT01529450 Pilot LDE225 in Locally Advanced or Metastatic BCC + Previously Tx Non-LDE225 Smoothened Inhibitors https://ClinicalTrials.gov/show/NCT01529450 Completed Stanford University 2013-08-31
NCT01482104 New Versus Approved Methyl-aminolevulinate Photodynamic Therapy (MAL-PDT) Regime in Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT01482104 Completed Norwegian University of Science and Technology 2017-10-31
NCT01463709 Development of a Nanosecond Pulsed Electric Field System to Treat Skin Cancer https://ClinicalTrials.gov/show/NCT01463709 Completed UCSF Benioff Children’s Hospital Oakland 2012-06-30
NCT01455363 Post-occlusive Reactive Hyperemia and Basal-cell Carcinoma https://ClinicalTrials.gov/show/NCT01455363 Completed Institut Curie 2011-10-31
NCT01367665 STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01367665 Completed Hoffmann-La Roche 2017-06-14
NCT01358045 Topical Vitamin D3, Diclofenac or a Combination of Both to Treat Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01358045 Completed Maastricht University Medical Center 2013-02-28
NCT01350115 Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS) https://ClinicalTrials.gov/show/NCT01350115 Completed Novartis 2012-10-31
NCT01327053 A Phase II Study of Efficacy and Safety in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01327053 Completed Novartis 2013-06-28
NCT01325688 PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities https://ClinicalTrials.gov/show/NCT01325688 Completed Peplin 2012-03-31
NCT04389112 Study of Metabolic Changes in the Transformation Malignant Precancerous Skin Lesions https://ClinicalTrials.gov/show/NCT04389112 Recruiting University Hospital, Bordeaux 2021-02-28
NCT04279535 Topical Vitamin C for Treatment of Basal Cell Cancer https://ClinicalTrials.gov/show/NCT04279535 Completed Center for Biomedical Research, Inc. 2019-03-01
NCT04155190 An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC https://ClinicalTrials.gov/show/NCT04155190 Recruiting PellePharm, Inc. 2020-06-30
NCT04124796 Identification of Psychosocial Factors Associated With Diagnostic Delay in Advanced Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT04124796 Completed University Hospital, Bordeaux 2019-11-12
NCT04093401 The VIDYA Study-designed to Determine if Patients With a History of Basal Cell Carcinoma Are More Inclined to Return for Follow-up if Their Risk of a Subsequent Basal Cell Carcinoma is Quantitated. https://ClinicalTrials.gov/show/NCT04093401 Recruiting University of Wisconsin, Madison 2020-10-31
NCT03972748 Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin. https://ClinicalTrials.gov/show/NCT03972748 Recruiting Hospital de Clinicas de Porto Alegre 2020-12-01
NCT03848078 (Cost)-Effectiveness of Optical Coherence Tomography (OCT) in Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT03848078 Recruiting Maastricht University Medical Center 2021-02-26
NCT03816332 Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers https://ClinicalTrials.gov/show/NCT03816332 Recruiting National Cancer Institute (NCI) 2021-05-30
NCT03775525 Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or Lymphoma https://ClinicalTrials.gov/show/NCT03775525 Recruiting Genzada Pharmaceuticals USA, Inc. 2020-09-30
NCT03769285 Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial https://ClinicalTrials.gov/show/NCT03769285 Recruiting Women’s College Hospital 2020-12-31
NCT03742726 Study Assessing the Safety and Performance of Smart Matrix® https://ClinicalTrials.gov/show/NCT03742726 Recruiting Smart Matrix Limited 2021-02-28
NCT03714529 A Study of IO103 in Montanide Adjuvant for Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT03714529 Recruiting Herlev and Gentofte Hospital 2019-01-15
NCT03703310 Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome) https://ClinicalTrials.gov/show/NCT03703310 Active, not recruiting PellePharm, Inc. 2020-12-06
NCT03646188 Open-Label Dose Escalation Trial to Evaluate Dose Limiting Toxicity and Maximum Tolerated Dose of Microneedle Arrays Containing Doxorubicin (D-MNA) in BCC https://ClinicalTrials.gov/show/NCT03646188 Recruiting SkinJect, Inc. 2020-12-01
NCT03610620 Confocal Microscopy Evaluation of Margin Clearance in Basal Cell Carcinomas in Mohs Surgery https://ClinicalTrials.gov/show/NCT03610620 Completed Norfolk and Norwich University Hospitals NHS Foundation Trust 2018-08-09
NCT03610022 Relationship Between Pharmacokinetics and Safety of Vismodegib - OPTIVISMO-1 https://ClinicalTrials.gov/show/NCT03610022 Recruiting University Hospital, Bordeaux 2020-11-30
NCT03573401 Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT). https://ClinicalTrials.gov/show/NCT03573401 Recruiting Biofrontera Bioscience GmbH 2021-07-31
NCT03569345 Basal Cell Carcinomas Treated With Ablative Fractional Laser and Ingenol Mebutate https://ClinicalTrials.gov/show/NCT03569345 Completed Bispebjerg Hospital 2018-05-18
NCT03541252 Topical Laser-assisted Combination Chemotherapy for Basal Cell Carcinoma― a Clinical Study https://ClinicalTrials.gov/show/NCT03541252 Recruiting Bispebjerg Hospital 2019-01-31
NCT03534947 A Study to Evaluate Neoadjuvant Sonidegib Followed by Surgery or Imiquimod in the Management of Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT03534947 Recruiting Melanoma Institute Australia 2020-12-31
NCT03521830 Nivolumab Alone or Plus Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT03521830 Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 2023-11-30
NCT03517488 A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors https://ClinicalTrials.gov/show/NCT03517488 Recruiting Xencor, Inc. 2020-12-31
NCT03509467 Using MC1R Genotype to Impact Melanoma Risk Behavior https://ClinicalTrials.gov/show/NCT03509467 Active, not recruiting H. Lee Moffitt Cancer Center and Research Institute 2020-11-30
NCT03483441 Vitamin D and Photodynamic Therapy for Treatment of BCC in BCNS https://ClinicalTrials.gov/show/NCT03483441 Recruiting The Cleveland Clinic 2022-05-01
NCT03467789 Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT03467789 Recruiting Case Comprehensive Cancer Center 2021-11-30
NCT03458117 T-VEC in Non-melanoma Skin Cancer https://ClinicalTrials.gov/show/NCT03458117 Recruiting University of Zurich 2020-02-29
NCT01770002 Eversion in Dermatologic Surgery: Is Cosmetic Appearance Improved? https://ClinicalTrials.gov/show/NCT01770002 Completed University of California, Davis 2013-09-30
NCT01260987 Fractional CO2 Laser Assisted Photodynamic Therapy https://ClinicalTrials.gov/show/NCT01260987 Completed Bispebjerg Hospital 2012-08-31
NCT01245972 Pilot Study of PDL to Treat BCC and SCCIS https://ClinicalTrials.gov/show/NCT01245972 Completed University of California, San Diego 2011-06-30
NCT01212549 Comparison of Two Schemes of Cryosurgery and Imiquimod Combination Treatment for Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01212549 Completed University of Ioannina 2010-01-31
NCT01208831 An East Asian Study of LDE225 https://ClinicalTrials.gov/show/NCT01208831 Completed Novartis 2013-10-31
NCT01204073 A Study of TAK-441 in Adult Patients With Advanced Nonhematologic Malignancies https://ClinicalTrials.gov/show/NCT01204073 Completed Millennium Pharmaceuticals, Inc. 2012-12-31
NCT01201915 A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449) in Operable Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01201915 Completed Genentech, Inc. 2013-05-31
NCT01155609 L-lysine in Treating Oral Mucositis in Patients Undergoing Radiation Therapy With or Without Chemotherapy For Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01155609 Completed University of Washington 2011-12-31
NCT01108094 Pilot Biomarker Trial to Evaluate the Efficacy of Itraconazole in Patients w/ Basal Cell Carcinomas https://ClinicalTrials.gov/show/NCT01108094 Completed Stanford University 2011-03-31
NCT01106508 A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors https://ClinicalTrials.gov/show/NCT01106508 Completed Novartis 2015-06-30
NCT01015898 Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01015898 Completed Shahid Beheshti University of Medical Sciences 2008-07-31
NCT00988455 Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma With 6 Months Follow-up https://ClinicalTrials.gov/show/NCT00988455 Completed Shahid Beheshti University of Medical Sciences 2009-03-31
NCT00985829 Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00985829 Completed Shahid Beheshti University of Medical Sciences 2008-07-31
NCT00961896 A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients https://ClinicalTrials.gov/show/NCT00961896 Completed Novartis 2010-08-31
NCT00959647 A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study https://ClinicalTrials.gov/show/NCT00959647 Completed Genentech, Inc. 2014-01-31
NCT00880308 Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors https://ClinicalTrials.gov/show/NCT00880308 Completed Novartis 2013-07-31
NCT00847912 CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial https://ClinicalTrials.gov/show/NCT00847912 Completed VA Office of Research and Development 2013-06-28
NCT03982212 A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors https://ClinicalTrials.gov/show/NCT03982212 Recruiting University of Kansas Medical Center 2020-07-31
NCT00833417 A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients With Advanced Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00833417 Completed Genentech, Inc. 2010-11-30
NCT03734913 A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors https://ClinicalTrials.gov/show/NCT03734913 Recruiting Guangdong Zhongsheng Pharmaceutical Co., Ltd. 2020-11-01
NCT02579551 Effectiveness of Narrow Margins in Patients With Low-Risk Basal Cell Carcinoma Undergoing Surgery https://ClinicalTrials.gov/show/NCT02579551 Completed Thomas Jefferson University 2014-02-01
NCT02834013 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors https://ClinicalTrials.gov/show/NCT02834013 Recruiting National Cancer Institute (NCI) 2021-08-31
NCT02158650 Video-Based Treatment Options for Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT02158650 Completed Emory University 2015-08-31
NCT04229277 Fast Track Diagnosis of Skin Cancer by Advanced Imaging https://ClinicalTrials.gov/show/NCT04229277 Active, not recruiting University Hospital Bispebjerg and Frederiksberg 2020-03-22
NCT00765193 The Impact of Total Body Skin Examination on Skin Cancer Detection https://ClinicalTrials.gov/show/NCT00765193 Completed Medical University of Graz 2009-05-31
NCT00670189 A Phase 1 Study of BMS-833923 (XL139) in Subjects With Advanced or Metastatic Cancer https://ClinicalTrials.gov/show/NCT00670189 Completed Bristol-Myers Squibb 2014-04-30
NCT00604890 Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00604890 Completed Berg, LLC 2010-01-31
NCT00586040 Photochemical Tissue Bonding https://ClinicalTrials.gov/show/NCT00586040 Completed Massachusetts General Hospital 2009-04-30
NCT00581425 Intron-A/Aldara Combination Therapy for Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT00581425 Completed The University of Texas Health Science Center, Houston 2011-09-30
NCT00578214 Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery https://ClinicalTrials.gov/show/NCT00578214 Completed Mayo Clinic 2008-04-30
NCT00571363 A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs’ Surgery of Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00571363 Completed NHS Tayside NA
NCT00492089 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00492089 Completed National Cancer Institute (NCI) 2010-08-31
NCT00473343 Metvix PDT in Patients With “High Risk” Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00473343 Completed Galderma NA
NCT00472459 PDT With Metvix® 160 mg/g Cream in Organ Transplant Recipients With Non-melanoma Skin Cancer https://ClinicalTrials.gov/show/NCT00472459 Completed Galderma NA
NCT00472108 Photodynamic Therapy (PDT) With Metvix Cream 160 mg/g Versus PDT With Placebo Cream in Patients With Primary Nodular Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00472108 Completed Galderma NA
NCT00472043 PDT With Metvix 160 mg/g Cream Versus PDT With Placebo Cream in Patients With Primary Nodular Basal Call Carcinoma https://ClinicalTrials.gov/show/NCT00472043 Completed Galderma NA
NCT00470496 Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00470496 Completed Roswell Park Cancer Institute 2011-10-28
NCT00469417 Metvix PDT Versus Cryotherapy in Patients With Primary Superficial Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00469417 Completed Galderma NA
NCT00432185 To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC https://ClinicalTrials.gov/show/NCT00432185 Completed Peplin 2010-03-31
NCT00374062 Effect of the Subconscious on Mohs Micrographic Surgery https://ClinicalTrials.gov/show/NCT00374062 Completed Northwestern University 2009-08-31
NCT00314756 Treatment of Nodular Basal Cell Carcinoma (BCC) With Imiquimod 5% Cream After Curettage https://ClinicalTrials.gov/show/NCT00314756 Completed Wake Forest University Health Sciences NA
NCT00237107 Debulking Effect of Curretage on Basal Cell Carcinomas - a Histological Assessment. https://ClinicalTrials.gov/show/NCT00237107 Completed Norwegian University of Science and Technology 2004-12-31
NCT00204555 Safety and Efficacy Study of Imiquimod 5% Cream Applied 3x Per Week for 8 or 12 Weeks in Low Risk Nodular Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00204555 Completed University Hospital Tuebingen NA
NCT00189306 Open-label Study to Evaluate Clearance of Superficial Basal Cell Carcinoma After Use of Imiquimod 5% Cream https://ClinicalTrials.gov/show/NCT00189306 Completed Graceway Pharmaceuticals, LLC 2007-04-30
NCT00189280 Aldara for the Treatment of Large and/or Multiple sBCC https://ClinicalTrials.gov/show/NCT00189280 Completed MEDA Pharma GmbH & Co. KG 2007-10-31
NCT00189241 A Study to Evaluate Effectiveness of Imiquimod 5% Cream in Superficial Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00189241 Completed MEDA Pharma GmbH & Co. KG 2007-02-28
NCT00188370 Ultrasound Biomicroscopy - Apoptosis https://ClinicalTrials.gov/show/NCT00188370 Completed University Health Network, Toronto NA
NCT00129519 A Study to Evaluate the Effectiveness of Imiquimod 5% Cream for Basal Cell Carcinoma Recurrence https://ClinicalTrials.gov/show/NCT00129519 Completed Graceway Pharmaceuticals, LLC 2006-01-31
NCT00108134 Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Superficial Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00108134 Completed Peplin 2006-03-31
NCT00108121 Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Nodular Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT00108121 Completed Peplin 2006-05-31
NCT00101348 Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT00101348 Completed National Cancer Institute (NCI) 2007-10-31
NCT00089362 Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors https://ClinicalTrials.gov/show/NCT00089362 Completed National Cancer Institute (NCI) 2008-01-31
NCT00089180 T4N5 Liposomal Lotion in Preventing The Recurrence of Nonmelanoma Skin Cancer in Patients Who Have Undergone a Kidney Transplant https://ClinicalTrials.gov/show/NCT00089180 Completed National Cancer Institute (NCI) 2007-01-31
NCT00068497 Gefitinib in Treating Patients With Metastatic or Unresectable Head and Neck Cancer or Non-Small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT00068497 Completed National Cancer Institute (NCI) 2007-12-31
NCT00031681 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) https://ClinicalTrials.gov/show/NCT00031681 Completed National Cancer Institute (NCI) 2011-01-31
NCT00030498 Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction https://ClinicalTrials.gov/show/NCT00030498 Completed National Cancer Institute (NCI) 2007-07-31
NCT00023959 Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer https://ClinicalTrials.gov/show/NCT00023959 Completed National Cancer Institute (NCI) 2010-03-31
NCT00007631 Determine the Efficacy of Topical Tretinoin Cream for the Prevention of Nonmelanoma Skin Cancer https://ClinicalTrials.gov/show/NCT00007631 Completed VA Office of Research and Development 2004-11-30
NCT00397384 Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer https://ClinicalTrials.gov/show/NCT00397384 Completed National Cancer Institute (NCI) 2013-06-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03370861 How Microbes and Metabolism May Predict Skin Cancer Immunotherapy Outcomes https://ClinicalTrials.gov/show/NCT03370861 Recruiting Washington University School of Medicine 2022-12-31
NCT03822988 ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTS https://ClinicalTrials.gov/show/NCT03822988 Recruiting Central Hospital, Nancy, France 2019-06-20
NCT03331874 RCM to Diagnose BCC - Reflectance Confocal Microscopy to Diagnose Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT03331874 Recruiting Norfolk and Norwich University Hospitals NHS Foundation Trust 2019-12-31
NCT03092830 Molecular Characterization of Cutaneous Tumors https://ClinicalTrials.gov/show/NCT03092830 Recruiting Rabin Medical Center 2020-08-07
NCT03050268 Familial Investigations of Childhood Cancer Predisposition https://ClinicalTrials.gov/show/NCT03050268 Recruiting St. Jude Children’s Research Hospital 2037-03-31
NCT02781389 Vismodegib on Locally Advanced Basal Cell Carcinoma Under Real World Conditions https://ClinicalTrials.gov/show/NCT02781389 Active, not recruiting University Hospital, Essen 2021-04-30
NCT02674009 Observational Study to Determine the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Locally Advanced Basal Cell Carcinoma (laBCC) https://ClinicalTrials.gov/show/NCT02674009 Completed Hoffmann-La Roche 2019-03-31
NCT00046189 Cancer Risk in Carriers of the Gene for Xeroderma Pigmentosum https://ClinicalTrials.gov/show/NCT00046189 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02438644 Observational Study of Vismodegib (Erivedge) in Patients Treated in Argentina https://ClinicalTrials.gov/show/NCT02438644 Completed Hoffmann-La Roche 2017-07-26
NCT02296970 An Observational Study to Determine the Clinical Cure Rate of Therapeutic up Front Shave Removal of Basal Cell Carcinoma of the Skin With Long Term Follow up to Evaluate Recurrence https://ClinicalTrials.gov/show/NCT02296970 Completed University of Pittsburgh 2016-06-30
NCT02100111 An Analysis of Treatment Patterns and Outcomes for Basal Cell Carcinoma (BCC) Cancer Participants https://ClinicalTrials.gov/show/NCT02100111 Completed Hoffmann-La Roche 2011-12-31
NCT01872130 Reflectance Confocal Microscopy of Wounds During Moh’s Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins https://ClinicalTrials.gov/show/NCT01872130 Completed Memorial Sloan Kettering Cancer Center 2020-04-28
NCT01540695 Does Cryofixation of Skin Specimens Affect Quality of Subsequent Formalin Fixed Paraffin Embedded H and E Histology https://ClinicalTrials.gov/show/NCT01540695 Completed Abramson Cancer Center of the University of Pennsylvania 2013-01-31
NCT01498250 Microarray Analysis of microRNA Expression in Basal Cell Carcinoma https://ClinicalTrials.gov/show/NCT01498250 Completed Ruhr University of Bochum 2011-12-31
NCT01403480 Rates of Positive Basal Cell Carcinomas (BCCs) in Re-excisions https://ClinicalTrials.gov/show/NCT01403480 Completed Rambam Health Care Campus 2010-12-31
NCT01370824 Clinical Diagnosis of Basal Cell Carcinoma Subtype https://ClinicalTrials.gov/show/NCT01370824 Completed Maastricht University Medical Center 2013-02-28
NCT04066504 Post-authorization Safety Study on the Long Term Safety of Sonidegib in Patients With Locally Advanced Cell Carcinoma https://ClinicalTrials.gov/show/NCT04066504 Recruiting Sun Pharmaceutical Industries Limited 2024-11-01
NCT03509415 Reflectance Confocal Microscopy to Diagnose BCC https://ClinicalTrials.gov/show/NCT03509415 Active, not recruiting Skin Care Network Ltd. 2019-02-28
NCT01212562 Treatment of Primary Basal Cell Carcinomas of the Skin With Combination of Topical Imiquimod and Cryosurgery https://ClinicalTrials.gov/show/NCT01212562 Completed University of Ioannina 2010-04-30
NCT01014819 A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions https://ClinicalTrials.gov/show/NCT01014819 Completed UCSF Benioff Children’s Hospital Oakland 2011-07-31
NCT00882791 Basal Cell Carcinoma Recurrence After Mohs Surgery https://ClinicalTrials.gov/show/NCT00882791 Completed Northwestern University 2009-05-31
NCT00875381 Analysis of Melanocytes (Pigment Cells) in Sun-Exposed Skin https://ClinicalTrials.gov/show/NCT00875381 Completed Mayo Clinic 2007-12-31
NCT03210935 French National Database of Rare Dermatological Cancers https://ClinicalTrials.gov/show/NCT03210935 Recruiting University Hospital, Lille 2025-12-31
NCT02371967 A Study to Assess the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Advanced Basal Cell Carcinoma (BCC) https://ClinicalTrials.gov/show/NCT02371967 Active, not recruiting Hoffmann-La Roche 2020-08-29
NCT00793169 Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery https://ClinicalTrials.gov/show/NCT00793169 Completed Northwestern University 2008-07-31
NCT00601185 Confocal Reflectance Microscopy of Shave-Biopsy Sites on Skin in Vivo. https://ClinicalTrials.gov/show/NCT00601185 Completed Memorial Sloan Kettering Cancer Center 2018-02-23
NCT00574392 Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo https://ClinicalTrials.gov/show/NCT00574392 Completed Memorial Sloan Kettering Cancer Center 2013-09-30
NCT00540566 Optical Biopsy of Human Skin in Conjunction With Laser Treatment https://ClinicalTrials.gov/show/NCT00540566 Completed University of California, Irvine 2008-06-30
NCT00218868 Cytodiagnosis of Basal Cell Carcinoma and Actinic Keratosis Using Papanicolaou and May-grunwald-giemsa Stained Tissue Smear https://ClinicalTrials.gov/show/NCT00218868 Completed Norwegian University of Science and Technology 2006-02-28
NCT00218829 DMSO-PDT of BCC - A 6 Year Follow up https://ClinicalTrials.gov/show/NCT00218829 Completed Norwegian University of Science and Technology 2004-12-31
NCT00836342 Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer https://ClinicalTrials.gov/show/NCT00836342 Completed Massachusetts General Hospital 2012-01-31
NCT00005660 The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases https://ClinicalTrials.gov/show/NCT00005660 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02310503 Spanish Registry of Mohs Surgery https://ClinicalTrials.gov/show/NCT02310503 Completed Fundación Academia Española de Dermatología 2020-02-29